Testing strategies for diagnosing lupus anticoagulant: Decision analysis
نویسندگان
چکیده
منابع مشابه
Trials and tribulations in lupus anticoagulant testing.
This issue of Clinical Chemistry and Laboratory Medicine includes a report by Pradella and colleagues regarding a cooperative multicentre study to define the upper limits of normal for several tests used in the diagnostic assessment of lupus anticoagulant (LA) [1] . In total, 200 normal samples were assessed, comprising 40 from each of five centres, for a total of six functional LA assays. Each...
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Interlaboratory and intermethod variation in commercial and in-house tests used for the measurement of anticardiolipin antibodies (aCL) and lupus anticoagulant (LA) limit the diagnostic value of the results from these tests. This short review summarizes published and unpublished guidelines (some developed using consensus procedures) on aCL and LA testing that are aimed at decreasing assay varia...
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We have constructed a Bayesian influence diagram and implemented an analytic framework to recommend strategies for selecting prenatal diagnostic tests and deciding whether to terminate a pregnancy based on their results. Our model is an improvement over previous applications of decision analysis to prenatal testing because it includes multiple diseases (Down’s syndrome, neural-tube defects, cys...
متن کاملEpilepsy associated with lupus anticoagulant
INTRODUCTION Lupus anticoagulant (LA) is commonly present in patients with systemic lupus erythematosus (SLE) who present with an ischemic cerebral stroke. Reports have noted the presence of LA in patients with epilepsy who do not have SLE. These patients are usually elderly, and it has been postulated that their epilepsy is due to subclinical ischemic infarcts. METHODS Two cases are presente...
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Laboratory tests for lupus anticoagulants (LA) are commonly performed to evaluate thrombosis or suspected phospholipid antibody syndromes. To determine current LA testing practices, and if they conform to published recommendations, two questionnaires were distributed to clinical laboratory members of the North American Specialized Coagulation Laboratory Association (NASCOLA) and the ECAT Founda...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2002
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.10115